Discovery and speciesEdit
The genera Apatodontosaurus, Ancanamunia, Baptanodon, Mollesaurus, Paraophthalmosaurus, Undorosaurus and Yasykovia were all considered junior synonyms of Ophthalmosaurus by Maisch & Matzke, 2000. However, all recent cladistic analyses found that Mollesaurus periallus from Argentina is a valid genus of ophthalmosaurid. Ophthalmosaurus natans is probably not a species of Ophthalmosaurus either, for which the generic name Baptanodon Marsh, 1880 is available. Undorosaurus's validity is now accepted by most authors, even by Maisch (2010) who originally proposed the synonymy. and the two other Russian taxa might be also valid. Ophthalmosaurus chrisorum Russell, 1993 was moved to its own genus Arthropterygius in 2010 by Maxwell.
Within Ophthalmosauridae, Ophthalmosaurus was regarded to be most closely related to Aegirosaurus. However, many recent cladistic analyses found Ophthalmosaurus to nest in a clade with Acamptonectes and Mollesaurus. Aegirosaurus was found to be more closely related to Platypterygius, and thus it doesn't belong to the Ophthalmosaurinae.
Like other ichthyosaurs, Ophthalmosaurus gave birth to its pups tail-first to avoid drowning them. Skeletons of unhatched young have been found in over fifty females on fossil finds, and litter sizes ranged from two to eleven pups.
Ophthalmosaurus had a body shaped like a tear-drop and a caudal fin like a half-moon. Its forelimbs were more developed than the hind ones, which suggests that the front fins did the steering while the tail did the propelling. Ophthalmosaurus chief claim to fame is its eyes which, at 4 inches in diameter, were extremely large in proportion to its body. The eyes occupied almost all of the space in the skull and were protected by bony plates (sclerotic rings), which most likely assisted to maintain the shape of the eyeballs  against water pressure at depth. The size of the eyes and the sclerotic rings suggests that Ophthalmosaurus hunted at a depth where there is not much light or that it may have hunted at night when a prey species was more active.
Calculations suggest that a typical Ophthalmosaurus could stay submerged for approximately 20 minutes or more . The swimming speed of Ophthalmosaurus has been estimated at 2.5 m/s or greater, but even assuming a conservative speed of 1 m/s, an Ophthalmosaurus would be able to dive to 600 meters and return to the surface within 20 minutes.
In the bone joints of Ophthalmosaurus skeletons traces of decompression sickness (the bends) have been found, possibly caused as a result of evasive tactics. Modern whales have been known to get the bends when ascending rapidly to escape predators.